Necatorin
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Necatorin is a highly mutagenic chemical compound with the molecular formula C15H8N2O3. It is found in some mushrooms including Lactarius turpis (ugly milk-cap; older: L. necator), from which it was first isolated and characterized. It tests positive in the Ames test, an assay for mutagenicity. Crude extracts of L. necator are also highly mutagenic in a bacterial test system, and this effect it attributed to necatorin.
Necatorin is present in L. necator at concentrations of 3 to 20 mg/kg, and blanching the mushroom can reduce it to about 25% of its original amount. In boiling water, the chemical compound is stable except under acidic conditions (pH = 5).