Neohexene is the hydrocarbon compound with the chemical formula (CH3)3CCH=CH2. It is a colorless liquid, with properties similar to other hexenes. It is a precursor to commercial synthetic musk perfumes.

Preparation and reactions

Neohexene is prepared by ethenolysis of diisobutene, an example of a metathesis reaction:

(CH3)3C-CH=C(CH3)2 + CH2=CH2 → (CH3)3C-CH=CH2 + (CH3)2C=CH2

It is a building block to synthetic musks by its reaction with p-cymene. It is also used in the industrial preparation of terbinafine.

In the study of C-H activation, neohexene is often used as a hydrogen acceptor.