Ortueri is a comune (municipality) in the Province of Nuoro in the Italian region Sardinia, located about 90 kilometres (56 mi) north of Cagliari and about 45 kilometres (28 mi) southwest of Nuoro.

Ortueri borders the following municipalities: Austis, Busachi, Neoneli, Samugheo, Sorgono, Ula Tirso.