PIK3CB

Identifiers

Aliases, P110BETA, PI3K, PI3KBETA, PIK3C1, phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 3 (human)

Band 3q22.3 Start 138,652,698 bp

End138,834,928 bp

Gene location ( Mouse )

Chr.Chromosome 9 (mouse)

Band 9|9 E3.3 Start 98,918,707 bp

End99,022,674 bp

RNA expression pattern

HumanMouse (ortholog)tendon of biceps brachii internal globus pallidus endothelial cell middle temporal gyrus Epithelium of choroid plexus Brodmann area 23 lateral nuclear group of thalamus kidney tubule optic nerve ponsgranulocyte superior cervical ganglion esophagus interventricular septum zygote facial motor nucleus morula secondary oocyte lip dentate gyrus of hippocampal formation granule cell

Human Mouse (ortholog)

tendon of biceps brachii internal globus pallidus endothelial cell middle temporal gyrus Epithelium of choroid plexus Brodmann area 23 lateral nuclear group of thalamus kidney tubule optic nerve ponsgranulocyte superior cervical ganglion esophagus interventricular septum zygote facial motor nucleus morula secondary oocyte lip dentate gyrus of hippocampal formation granule cell

tendon of biceps brachii internal globus pallidus endothelial cell middle temporal gyrus Epithelium of choroid plexus Brodmann area 23 lateral nuclear group of thalamus kidney tubule optic nerve pons

granulocyte superior cervical ganglion esophagus interventricular septum zygote facial motor nucleus morula secondary oocyte lip dentate gyrus of hippocampal formation granule cell

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta isoform is an enzyme that in humans is encoded by the PIK3CB gene.

Phosphoinositide 3-kinases (PI3Ks) phosphorylate the 3-prime OH position of the inositol ring of inositol lipids. They have been implicated as participants in signaling pathways regulating cell growth by virtue of their activation in response to various mitogenic stimuli. PI3Ks are composed of a 110-kD catalytic subunit, such as PIK3CB, and an 85-kD adaptor subunit (Hu et al., 1993).[supplied by OMIM]

PIK3CB

Further reading