PDLIM5

Available structuresPDBOrtholog search:List of PDB id codes,

Available structures

PDBOrtholog search:

List of PDB id codes,

List of PDB id codes

Identifiers

Aliases, ENH, ENH1, LIM, L9, PDZ and LIM domain 5

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 4 (human)

Band 4q22.3 Start 94,451,857 bp

End94,668,227 bp

Gene location ( Mouse )

Chr.Chromosome 3 (mouse)

Band 3|3 H1 Start 141,945,351 bp

End142,101,457 bp

RNA expression pattern

HumanMouse (ortholog)Skeletal muscle tissue of biceps brachii Skeletal muscle tissue of rectus abdominis right ventricle triceps brachii muscle glutes thoracic diaphragm Epithelium of choroid plexus muscle of thigh gastrocnemius muscle body of tonguesoleus muscle myocardium of ventricle atrioventricular valve muscle of thigh quadriceps femoris muscle vastus lateralis muscle interventricular septum sternocleidomastoid muscle tibialis anterior muscle medial head of gastrocnemius muscle

Human Mouse (ortholog)

Skeletal muscle tissue of biceps brachii Skeletal muscle tissue of rectus abdominis right ventricle triceps brachii muscle glutes thoracic diaphragm Epithelium of choroid plexus muscle of thigh gastrocnemius muscle body of tonguesoleus muscle myocardium of ventricle atrioventricular valve muscle of thigh quadriceps femoris muscle vastus lateralis muscle interventricular septum sternocleidomastoid muscle tibialis anterior muscle medial head of gastrocnemius muscle

soleus muscle myocardium of ventricle atrioventricular valve muscle of thigh quadriceps femoris muscle vastus lateralis muscle interventricular septum sternocleidomastoid muscle tibialis anterior muscle medial head of gastrocnemius muscle

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

PDZ and LIM domain protein 5 is a protein that in humans is encoded by the PDLIM5 gene.

The protein encoded by this gene is a LIM domain protein. LIM domains are cysteine-rich double zinc fingers composed of 50 to 60 amino acids that are involved in protein-protein interactions. LIM domain-containing proteins are scaffolds for the formation of multiprotein complexes. The proteins are involved in cytoskeleton organization, cell lineage specification, organ development, and oncogenesis. The encoded protein is also a member of the Enigma class of proteins, a family of proteins that possess a 100-amino acid PDZ domain in the N-terminus and 1 to 3 LIM domains in the C terminus. Multiple transcript variants encoding different isoforms have been found for this gene, although not all of them have been fully characterized.

Interactions

PDLIM5 has been shown to interact with PRKCB1.

PDLIM5

Interactions

Further reading