PEX10

Identifiers

Aliases, NALD, PBD6A, PBD6B, RNF69, peroxisomal biogenesis factor 10

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p36.32 Start 2,403,964 bp

End2,413,797 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 E2 Start 155,151,473 bp

End155,156,890 bp

RNA expression pattern

HumanMouse (ortholog)parotid gland tendon of biceps brachii C1 segment right adrenal cortex left adrenal gland left adrenal cortex amygdala internal globus pallidus left testis right testisyolk sac hand aortic valve otolith organ utricle neural layer of retina muscle of thigh right kidney ascending aorta soleus muscle

Human Mouse (ortholog)

parotid gland tendon of biceps brachii C1 segment right adrenal cortex left adrenal gland left adrenal cortex amygdala internal globus pallidus left testis right testisyolk sac hand aortic valve otolith organ utricle neural layer of retina muscle of thigh right kidney ascending aorta soleus muscle

parotid gland tendon of biceps brachii C1 segment right adrenal cortex left adrenal gland left adrenal cortex amygdala internal globus pallidus left testis right testis

yolk sac hand aortic valve otolith organ utricle neural layer of retina muscle of thigh right kidney ascending aorta soleus muscle

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Peroxisome biogenesis factor 10 is a protein that in humans is encoded by the PEX10 gene. Alternative splicing results in two transcript variants encoding different isoforms.

Function

Peroxisome biogenesis factor 10 is involved in import of peroxisomal matrix proteins. This protein localizes to the peroxisomal membrane.

Clinical significance

Mutations in this gene result in phenotypes within the Zellweger spectrum of peroxisomal biogenesis disorders, ranging from neonatal adrenoleukodystrophy to Zellweger syndrome.

Interactions

PEX10 has been shown to interact with PEX12 and PEX19.

PEX10

Function

Clinical significance

Interactions

Further reading

External links