PHF21A

PHD finger protein 21A is a protein that in humans is encoded by the PHF21A gene.

Function

BHC80 is a component of a BRAF35 (MIM 605535)/histone deacetylase (HDAC; see MIM 601241) complex (BHC) that mediates repression of neuron-specific genes through the cis-regulatory element known as repressor element-1 (RE1) or neural restrictive silencer (NRS) (Hakimi et al., 2002).[supplied by OMIM]

Interactions

PHF21A has been shown to interact with:

• HDAC1,
• HMG20B,
• Histone deacetylase 2, and
• RCOR1.

Further reading

External links

• at the U.S. National Library of MedicineMedical Subject Headings(MeSH)

This article incorporates text from the United States National Library of Medicine, which is in the public domain.