PIGT

Identifiers

Aliases, MCAHS3, NDAP, PNH2, CGI-06, phosphatidylinositol glycan anchor biosynthesis class T

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 20 (human)

Band 20q13.12 Start 45,416,084 bp

End45,456,934 bp

Gene location ( Mouse )

Chr.Chromosome 2 (mouse)

Band 2|2 H3 Start 164,339,440 bp

End164,350,221 bp

RNA expression pattern

HumanMouse (ortholog)cardia stromal cell of endometrium pylorus right coronary artery Descending thoracic aorta ascending aorta right auricle of heart left coronary artery apex of heart islet of Langerhanstail of embryo lip neural layer of retina genital tubercle superior frontal gyrus dentate gyrus of hippocampal formation granule cell muscle of thigh ventricular zone primary visual cortex yolk sac

Human Mouse (ortholog)

cardia stromal cell of endometrium pylorus right coronary artery Descending thoracic aorta ascending aorta right auricle of heart left coronary artery apex of heart islet of Langerhanstail of embryo lip neural layer of retina genital tubercle superior frontal gyrus dentate gyrus of hippocampal formation granule cell muscle of thigh ventricular zone primary visual cortex yolk sac

cardia stromal cell of endometrium pylorus right coronary artery Descending thoracic aorta ascending aorta right auricle of heart left coronary artery apex of heart islet of Langerhans

tail of embryo lip neural layer of retina genital tubercle superior frontal gyrus dentate gyrus of hippocampal formation granule cell muscle of thigh ventricular zone primary visual cortex yolk sac

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

GPI transamidase component PIG-T is an enzyme that in humans is encoded by the PIGT gene.

This gene encodes a protein that is involved in glycosylphosphatidylinositol (GPI)-anchor biosynthesis. The GPI-anchor is a glycolipid found on many blood cells and serves to anchor proteins to the cell surface. This protein is an essential component of the multisubunit enzyme, GPI transamidase. GPI transamidase mediates GPI anchoring in the endoplasmic reticulum, by catalyzing the transfer of fully assembled GPI units to proteins.

Interactions

PIGT has been shown to interact with PIGK and GPAA1.

PIGT

Interactions

Further reading