POLDIP3

Identifiers

Aliases, PDIP46, SKAR, polymerase (DNA) delta interacting protein 3, DNA polymerase delta interacting protein 3, PDIP3

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 22 (human)

Band 22q13.2 Start 42,583,721 bp

End42,614,962 bp

Gene location ( Mouse )

Chr.Chromosome 15 (mouse)

Band 15|15 E1 Start 83,010,177 bp

End83,033,585 bp

RNA expression pattern

HumanMouse (ortholog)ventricular zone ganglionic eminence left ovary oocyte right ovary granulocyte right uterine tube islet of Langerhans cardia body of uterusinternal carotid artery external carotid artery motor neuron condyle Rostral migratory stream fossa medial ganglionic eminence ascending aorta aortic valve vestibular membrane of cochlear duct

Human Mouse (ortholog)

ventricular zone ganglionic eminence left ovary oocyte right ovary granulocyte right uterine tube islet of Langerhans cardia body of uterusinternal carotid artery external carotid artery motor neuron condyle Rostral migratory stream fossa medial ganglionic eminence ascending aorta aortic valve vestibular membrane of cochlear duct

ventricular zone ganglionic eminence left ovary oocyte right ovary granulocyte right uterine tube islet of Langerhans cardia body of uterus

internal carotid artery external carotid artery motor neuron condyle Rostral migratory stream fossa medial ganglionic eminence ascending aorta aortic valve vestibular membrane of cochlear duct

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Polymerase delta-interacting protein 3 is an enzyme that in humans is encoded by the POLDIP3 gene.

This gene encodes a protein that interacts with the DNA polymerase delta p50 subunit. This protein is a specific target of S6 kinase 1 and regulates cell growth. Two transcript variants that encode different protein isoforms have been identified.

Interactions

POLDIP3 has been shown to interact with P70-S6 Kinase 1.

POLDIP3

Interactions

Further reading