PPP1R3C

Identifiers

Aliases, PPP1R5, protein phosphatase 1 regulatory subunit 3C, PTG

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 10 (human)

Band 10q23.32 Start 91,628,442 bp

End91,633,071 bp

Gene location ( Mouse )

Chr.Chromosome 19 (mouse)

Band 19|19 C2 Start 36,709,131 bp

End36,714,053 bp

RNA expression pattern

HumanMouse (ortholog)Skeletal muscle tissue of rectus abdominis Skeletal muscle tissue of biceps brachii vastus lateralis muscle triceps brachii muscle body of tongue glutes deltoid muscle tibialis anterior muscle vena cava saphenous veinsternocleidomastoid muscle triceps brachii muscle muscle of thigh digastric muscle intercostal muscle temporal muscle vastus lateralis muscle left lung lobe medial head of gastrocnemius muscle atrioventricular valve

Human Mouse (ortholog)

Skeletal muscle tissue of rectus abdominis Skeletal muscle tissue of biceps brachii vastus lateralis muscle triceps brachii muscle body of tongue glutes deltoid muscle tibialis anterior muscle vena cava saphenous veinsternocleidomastoid muscle triceps brachii muscle muscle of thigh digastric muscle intercostal muscle temporal muscle vastus lateralis muscle left lung lobe medial head of gastrocnemius muscle atrioventricular valve

sternocleidomastoid muscle triceps brachii muscle muscle of thigh digastric muscle intercostal muscle temporal muscle vastus lateralis muscle left lung lobe medial head of gastrocnemius muscle atrioventricular valve

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Protein phosphatase 1 regulatory subunit 3C also known as PTG is an enzyme that in humans is encoded by the PPP1R3C gene.

Function

Protein phosphatase-1 (PP1) participates in the regulation of a wide variety of cellular functions by reversible protein phosphorylation. The ability of PP1 to regulate diverse functions resides in its capacity to interact with a variety of regulatory subunits that may target PP1 to specific subcellular locations, modulate its substrate specificity, and allow its activity to be responsive to extracellular signals. Several targeting subunits of PP1 have been identified, including PPP1R5, the glycogen-binding subunits GM, GL, PTG and R6 and PPP1R4, and the nuclear inhibitor of PP1 (PPP1R8).

PPP1R3C

Function

Further reading