PPP2R2C

Identifiers

Aliases, B55-GAMMA, IMYPNO, IMYPNO1, PR52, PR55G, protein phosphatase 2 regulatory subunit Bgamma, B55gamma

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 4 (human)

Band 4p16.1 Start 6,320,578 bp

End6,563,600 bp

Gene location ( Mouse )

Chr.Chromosome 5 (mouse)

Band 5|5 B3 Start 37,025,857 bp

End37,112,422 bp

RNA expression patternHumanMouse (ortholog)middle temporal gyrus Brodmann area 46 superior frontal gyrus parietal lobe postcentral gyrus occipital lobe Brodmann area 23 entorhinal cortex primary visual cortex prefrontal cortexvisual cortex superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell primary motor cortex piriform cortex prefrontal cortex cingulate gyrus olfactory tubercle cerebellar cortexn/a

RNA expression pattern

HumanMouse (ortholog)middle temporal gyrus Brodmann area 46 superior frontal gyrus parietal lobe postcentral gyrus occipital lobe Brodmann area 23 entorhinal cortex primary visual cortex prefrontal cortexvisual cortex superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell primary motor cortex piriform cortex prefrontal cortex cingulate gyrus olfactory tubercle cerebellar cortex

Human Mouse (ortholog)

middle temporal gyrus Brodmann area 46 superior frontal gyrus parietal lobe postcentral gyrus occipital lobe Brodmann area 23 entorhinal cortex primary visual cortex prefrontal cortexvisual cortex superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell primary motor cortex piriform cortex prefrontal cortex cingulate gyrus olfactory tubercle cerebellar cortex

middle temporal gyrus Brodmann area 46 superior frontal gyrus parietal lobe postcentral gyrus occipital lobe Brodmann area 23 entorhinal cortex primary visual cortex prefrontal cortex

visual cortex superior frontal gyrus primary visual cortex dentate gyrus of hippocampal formation granule cell primary motor cortex piriform cortex prefrontal cortex cingulate gyrus olfactory tubercle cerebellar cortex

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B gamma isoform is an enzyme that in humans is encoded by the PPP2R2C gene.

Function

The product of this gene belongs to the phosphatase 2 regulatory subunit B family. Protein phosphatase 2 is one of the four major Ser/Thr phosphatases, and it is implicated in the negative control of cell growth and division. It consists of a common heteromeric core enzyme, which is composed of a catalytic subunit and a constant regulatory subunit, that associates with a variety of regulatory subunits. The B regulatory subunit might modulate substrate selectivity and catalytic activity. This gene encodes a gamma isoform of the regulatory subunit B55 subfamily. Alternatively spliced transcript variants encoding different isoforms have been identified.

PPP2R2C

Function

Further reading