Paxtachi District is a district of Samarqand Region in Uzbekistan. The capital lies at the town Ziyovuddin. It has an area of 1,380km2(530sqmi) and its population is 146,000 (2021 est.).

The district consists of 7 urban-type settlements (Ziyovuddin, Qodirist, Past Burkut, Sanchiqul, Suluvqoʻrgʻon, Urgich, Xumor) and 8 rural communities.

40°01′47″N 65°39′59″E/40.02972°N 65.66639°E/ 40.02972; 65.66639