Pythium debaryanum is a species of water mould in the family Pythiaceae. It is known as a plant pathogen on many kinds of wild and cultivated plants, including peanut, beet, eucalyptus, tobacco, and pine trees. The plants develop damping off, a disease state.

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Photographs enlarged from portions of a motion photomicrograph, showing the method of cell wall penetration by Pythium hyphae. A. — Shows the hypha growing against the potato cell wall. Sufficient pressure has already been applied to cause the hypha to bend. Notice that this bending increases in later photographs. B. — A little later stage than A. C. — The tip has broken through as a small tube D. — Penetration is complete. Notice the constriction of the hypha at the point where it penetrates the potato cell wall.