RGS11

Identifiers

Aliases, RS11, regulator of G-protein signaling 11, regulator of G protein signaling 11

External IDsOMIM: ; MGI: ; GeneCards:

Gene location ( Human )

Chr.Chromosome 16 (human)

Band 16p13.3 Start 268,301 bp

End275,980 bp

Gene location ( Mouse )

Chr.Chromosome 17 (mouse)

Band 17|17 A3.3 Start 26,421,925 bp

End26,430,298 bp

RNA expression pattern

HumanMouse (ortholog)right hemisphere of cerebellum right frontal lobe anterior pituitary C1 segment cingulate gyrus anterior cingulate cortex tibial nerve amygdala Brodmann area 9 apex of heartneural layer of retina superior frontal gyrus morula primary visual cortex islet of Langerhans adrenal gland ganglion of vagus nerve autonomic nerve plexus CA3 field stomach

Human Mouse (ortholog)

right hemisphere of cerebellum right frontal lobe anterior pituitary C1 segment cingulate gyrus anterior cingulate cortex tibial nerve amygdala Brodmann area 9 apex of heartneural layer of retina superior frontal gyrus morula primary visual cortex islet of Langerhans adrenal gland ganglion of vagus nerve autonomic nerve plexus CA3 field stomach

right hemisphere of cerebellum right frontal lobe anterior pituitary C1 segment cingulate gyrus anterior cingulate cortex tibial nerve amygdala Brodmann area 9 apex of heart

neural layer of retina superior frontal gyrus morula primary visual cortex islet of Langerhans adrenal gland ganglion of vagus nerve autonomic nerve plexus CA3 field stomach

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsDatabasesNCBI: ; OMA:SpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

DatabasesNCBI: ; OMA:

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Regulator of G-protein signaling 11 is a protein that in humans is encoded by the RGS11 gene.

The protein encoded by this gene belongs to the RGS (regulator of G protein signaling) family. Members of the RGS family act as GTPase-activating proteins on the alpha subunits of heterotrimeric, signal-transducing G proteins. This protein inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits, thereby driving them into their inactive GDP-bound form. Alternative splicing occurs at this locus and two transcript variants encoding distinct isoforms have been identified.

RGS11

Further reading