SF3A3

Available structuresPDBOrtholog search:List of PDB id codes

Available structures

PDBOrtholog search:

List of PDB id codes

Identifiers

Aliases, PRP9, PRPF9, SAP61, SF3a60, splicing factor 3a subunit 3

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p34.3 Start 37,956,975 bp

End37,990,075 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 D2.2 Start 124,608,569 bp

End124,626,253 bp

RNA expression pattern

HumanMouse (ortholog)sural nerve Achilles tendon epithelium of colon ganglionic eminence ventricular zone monocyte rectum gastrocnemius muscle islet of Langerhans stromal cell of endometriumotic placode saccule otic vesicle primitive streak tail of embryo abdominal wall epiblast embryo primary oocyte mandibular prominence

Human Mouse (ortholog)

sural nerve Achilles tendon epithelium of colon ganglionic eminence ventricular zone monocyte rectum gastrocnemius muscle islet of Langerhans stromal cell of endometriumotic placode saccule otic vesicle primitive streak tail of embryo abdominal wall epiblast embryo primary oocyte mandibular prominence

sural nerve Achilles tendon epithelium of colon ganglionic eminence ventricular zone monocyte rectum gastrocnemius muscle islet of Langerhans stromal cell of endometrium

otic placode saccule otic vesicle primitive streak tail of embryo abdominal wall epiblast embryo primary oocyte mandibular prominence

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Splicing factor 3A subunit 3 is a protein that in humans is encoded by the SF3A3 gene.

This gene encodes subunit 3 of the splicing factor 3a protein complex. The splicing factor 3a heterotrimer includes subunits 1, 2 and 3 and is necessary for the in vitro conversion of 15S U2 snRNP into an active 17S particle that performs pre-mRNA splicing. Subunit 3 interacts with subunit 1 through its amino-terminus while the zinc finger domain of subunit 3 plays a role in its binding to the 15S U2 snRNP. This gene has a pseudogene on chromosome 20.

Interactions

SF3A3 has been shown to interact with SF3A1.

SF3A3

Interactions

Further reading