SF3B6

Available structuresPDBOrtholog search:List of PDB id codes, , ,

Available structures

PDBOrtholog search:

List of PDB id codes, , ,

List of PDB id codes

, , ,

Identifiers

Aliases, HSPC175, Ht006, P14, SAP14, SAP14a, SF3B14, SF3B14a, CGI-110, splicing factor 3b subunit 6

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 2 (human)

Band 2p23.3 Start 24,067,586 bp

End24,076,373 bp

Gene location ( Mouse )

Chr.Chromosome 12 (mouse)

Band 12|12 A1.1 Start 4,867,544 bp

End4,877,659 bp

RNA expression patternHumanMouse (ortholog)skin of arm mucosa of ileum olfactory zone of nasal mucosa Achilles tendon mucosa of sigmoid colon ganglionic eminence cartilage tissue islet of Langerhans rectum tibialis anterior musclesaccule otic placode otic vesicle medial ganglionic eminence transitional epithelium of urinary bladder migratory enteric neural crest cell abdominal wall cervix endocardial cushion ventricular zonen/a

RNA expression pattern

HumanMouse (ortholog)skin of arm mucosa of ileum olfactory zone of nasal mucosa Achilles tendon mucosa of sigmoid colon ganglionic eminence cartilage tissue islet of Langerhans rectum tibialis anterior musclesaccule otic placode otic vesicle medial ganglionic eminence transitional epithelium of urinary bladder migratory enteric neural crest cell abdominal wall cervix endocardial cushion ventricular zone

Human Mouse (ortholog)

skin of arm mucosa of ileum olfactory zone of nasal mucosa Achilles tendon mucosa of sigmoid colon ganglionic eminence cartilage tissue islet of Langerhans rectum tibialis anterior musclesaccule otic placode otic vesicle medial ganglionic eminence transitional epithelium of urinary bladder migratory enteric neural crest cell abdominal wall cervix endocardial cushion ventricular zone

skin of arm mucosa of ileum olfactory zone of nasal mucosa Achilles tendon mucosa of sigmoid colon ganglionic eminence cartilage tissue islet of Langerhans rectum tibialis anterior muscle

saccule otic placode otic vesicle medial ganglionic eminence transitional epithelium of urinary bladder migratory enteric neural crest cell abdominal wall cervix endocardial cushion ventricular zone

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Splicing factor 3B subunit 6, is a protein encoded by SF3B6 gene in vertebrates.

Function

This gene encodes a 14 kDa protein subunit of the splicing factor 3b complex. Splicing factor 3b associates with both the U2 and U11/U12 small nuclear ribonucleoprotein complexes (U2 snRNP) of spliceosomes. This 14 kDa protein interacts directly with subunit 1 of the splicing factor 3b complex. This 14 kDa protein also interacts directly with the adenosine that carries out the first transesterification step of splicing at the pre-mRNA branch site.

Interactions

SF3B14 has been shown to interact with SF3B1.

SF3B6

Function

Interactions

Further reading