SH2D1B

Identifiers

Aliases, EAT2, SH2 domain containing 1B

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1q23.3 Start 162,395,268 bp

End162,412,138 bp

Gene location ( Mouse )

Chr.Chromosome 1 (mouse)

Band 1|1 H3 Start 170,104,889 bp

End170,114,338 bp

RNA expression patternHumanMouse (ortholog)granulocyte gastrocnemius muscle blood testicle sperm muscle of thigh monocyte amniotic fluid deltoid muscle spleenspleen granulocyte lung jejunum bone marrow ileum choroid plexus prefrontal cortex medulla oblongata superior colliculusn/a

RNA expression pattern

HumanMouse (ortholog)granulocyte gastrocnemius muscle blood testicle sperm muscle of thigh monocyte amniotic fluid deltoid muscle spleenspleen granulocyte lung jejunum bone marrow ileum choroid plexus prefrontal cortex medulla oblongata superior colliculus

Human Mouse (ortholog)

granulocyte gastrocnemius muscle blood testicle sperm muscle of thigh monocyte amniotic fluid deltoid muscle spleenspleen granulocyte lung jejunum bone marrow ileum choroid plexus prefrontal cortex medulla oblongata superior colliculus

granulocyte gastrocnemius muscle blood testicle sperm muscle of thigh monocyte amniotic fluid deltoid muscle spleen

spleen granulocyte lung jejunum bone marrow ileum choroid plexus prefrontal cortex medulla oblongata superior colliculus

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

SH2 domain-containing protein 1B is a protein that in humans is encoded by the SH2D1B gene.

By binding phosphotyrosines through its free SRC (MIM 190090) homology-2 (SH2) domain, EAT2 regulates signal transduction through receptors expressed on the surface of antigen-presenting cells (Morra et al., 2001).[supplied by OMIM]

Interactions

SH2D1B has been shown to interact with SLAMF1.

SH2D1B

Interactions

Further reading