SLA2

Available structuresPDBOrtholog search:List of PDB id codes

Available structures

PDBOrtholog search:

List of PDB id codes

Identifiers

Aliases, C20orf156, MARS, SLAP-2, SLAP2, Src-like-adaptor 2, Src like adaptor 2

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 20 (human)

Band 20q11.23 Start 36,612,318 bp

End36,646,196 bp

Gene location ( Mouse )

Chr.Chromosome 2 (mouse)

Band 2|2 H1 Start 156,714,377 bp

End156,729,112 bp

RNA expression patternHumanMouse (ortholog)buccal mucosa cell granulocyte monocyte blood testicle lymph node spleen appendix oocyte bone marrow cellthymus zygote primary oocyte secondary oocyte granulocyte embryo blood embryo pharynx morulan/a

RNA expression pattern

HumanMouse (ortholog)buccal mucosa cell granulocyte monocyte blood testicle lymph node spleen appendix oocyte bone marrow cellthymus zygote primary oocyte secondary oocyte granulocyte embryo blood embryo pharynx morula

Human Mouse (ortholog)

buccal mucosa cell granulocyte monocyte blood testicle lymph node spleen appendix oocyte bone marrow cellthymus zygote primary oocyte secondary oocyte granulocyte embryo blood embryo pharynx morula

buccal mucosa cell granulocyte monocyte blood testicle lymph node spleen appendix oocyte bone marrow cell

thymus zygote primary oocyte secondary oocyte granulocyte embryo blood embryo pharynx morula

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Src-like-adapter 2 is a protein that in humans is encoded by the SLA2 gene.

Function

This gene encodes a member of the SLAP family of adapter proteins. The encoded protein may play an important receptor-proximal role in downregulating T and B cell-mediated responses and inhibits antigen receptor-induced calcium mobilization. This protein interacts with Cas-Br-M (murine) ecotropic retroviral transforming sequence c. Two transcript variants encoding distinct isoforms have been identified for this gene.

Interactions

SLA2 has been shown to interact with Cbl gene.

SLA2

Function

Interactions

Further reading