Zinc transporter 3

SLC30A3

Identifiers

Aliases, ZNT3, solute carrier family 30 member 3

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 2 (human)

Band 2p23.3 Start 27,253,684 bp

End27,275,817 bp

Gene location ( Mouse )

Chr.Chromosome 5 (mouse)

Band 5 B1|5 16.97 cM Start 31,243,450 bp

End31,265,581 bp

RNA expression patternHumanMouse (ortholog)corpus epididymis Brodmann area 10 left testis right testis endothelial cell right frontal lobe dorsolateral prefrontal cortex Brodmann area 9 Brodmann area 46 middle temporal gyrusentorhinal cortex perirhinal cortex zygote CA3 field visual cortex primary visual cortex secondary oocyte superior frontal gyrus dentate gyrus of hippocampal formation granule cell Ileal epitheliumn/a

RNA expression pattern

HumanMouse (ortholog)corpus epididymis Brodmann area 10 left testis right testis endothelial cell right frontal lobe dorsolateral prefrontal cortex Brodmann area 9 Brodmann area 46 middle temporal gyrusentorhinal cortex perirhinal cortex zygote CA3 field visual cortex primary visual cortex secondary oocyte superior frontal gyrus dentate gyrus of hippocampal formation granule cell Ileal epithelium

Human Mouse (ortholog)

corpus epididymis Brodmann area 10 left testis right testis endothelial cell right frontal lobe dorsolateral prefrontal cortex Brodmann area 9 Brodmann area 46 middle temporal gyrusentorhinal cortex perirhinal cortex zygote CA3 field visual cortex primary visual cortex secondary oocyte superior frontal gyrus dentate gyrus of hippocampal formation granule cell Ileal epithelium

corpus epididymis Brodmann area 10 left testis right testis endothelial cell right frontal lobe dorsolateral prefrontal cortex Brodmann area 9 Brodmann area 46 middle temporal gyrus

entorhinal cortex perirhinal cortex zygote CA3 field visual cortex primary visual cortex secondary oocyte superior frontal gyrus dentate gyrus of hippocampal formation granule cell Ileal epithelium

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Zinc transporter 3 also known as solute carrier family 30 member 3 is a protein in humans that is encoded by the SLC30A3 gene.

The SLC30A3 gene codes for the ZnT-3 SLC30A family membrane transport protein. ZnT-3 is required for the accumulation of zinc ions inside synaptic vesicles. In mice, ZnT-3 is required for some forms of memory that depend on the hippocampus and the amygdala. Zinc transport by ZnT-3 modulates memory formation by acting through the extracellular signal-regulated kinases signaling pathway. Angiotensin II-induced senescence of vascular smooth muscle cells requires down-regulation of ZnT-3 and ZnT-10.

Zinc transporter 3

See also