Solute carrier organic anion transporter family member 2A1, also known as the prostaglandin transporter (PGT), is a protein that in humans is encoded by the SLCO2A1 gene.

This gene encodes a prostaglandin transporter that is a member of the 12-membrane-spanning organic anion-transporting polypeptide superfamily of transporters. The encoded protein may be involved in mediating the uptake and clearance of prostaglandins in numerous tissues.

Clinical relevance

Mutations in this gene have been shown to cause primary hypertrophic osteoarthropathy, specific form of chronic enteropathy.

Further reading

External links

  • Overview of all the structural information available in thePDBforUniProt:(Solute carrier organic anion transporter family member 2A1) at thePDBe-KB.

This article incorporates text from the United States National Library of Medicine, which is in the public domain.