SOCS4

Suppressor of cytokine signaling 4 is a protein that in humans is encoded by the SOCS4 gene.

Function

The protein encoded by this gene contains a SH2 domain and a SOCS BOX domain. The protein thus belongs to the suppressor of cytokine signaling (SOCS), also known as STAT-induced STAT inhibitor (SSI), protein family. SOCS family members are known to be cytokine-inducible negative regulators of cytokine signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.

External links

• provides an overview of all the structure information available in the PDB for Human Suppressor of cytokine signaling 4 (SOCS4)