SSH1

Identifiers

Aliases, SSH1L, slingshot protein phosphatase 1

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 12 (human)

Band 12q24.11 Start 108,778,191 bp

End108,857,590 bp

Gene location ( Mouse )

Chr.Chromosome 5 (mouse)

Band 5|5 F Start 114,075,155 bp

End114,131,955 bp

RNA expression pattern

HumanMouse (ortholog)sural nerve stromal cell of endometrium saphenous vein secondary oocyte trigeminal ganglion lower lobe of lung lactiferous duct tail of epididymis spinal ganglia caput epididymisinternal carotid artery Rostral migratory stream external carotid artery sciatic nerve substantia nigra fossa blood Gonadal ridge ciliary body cumulus cell

Human Mouse (ortholog)

sural nerve stromal cell of endometrium saphenous vein secondary oocyte trigeminal ganglion lower lobe of lung lactiferous duct tail of epididymis spinal ganglia caput epididymisinternal carotid artery Rostral migratory stream external carotid artery sciatic nerve substantia nigra fossa blood Gonadal ridge ciliary body cumulus cell

sural nerve stromal cell of endometrium saphenous vein secondary oocyte trigeminal ganglion lower lobe of lung lactiferous duct tail of epididymis spinal ganglia caput epididymis

internal carotid artery Rostral migratory stream external carotid artery sciatic nerve substantia nigra fossa blood Gonadal ridge ciliary body cumulus cell

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

For the SSH-1 protocol, see Secure Shell#Version 1

Protein phosphatase Slingshot homolog 1 is an enzyme that in humans is encoded by the SSH1 gene.

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002).[supplied by OMIM]

SSH1

Further reading