SSH2

Available structuresPDBOrtholog search:List of PDB id codes

Available structures

PDBOrtholog search:

List of PDB id codes

Identifiers

Aliases, SSH-2, SSH-2L, slingshot protein phosphatase 2

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 17 (human)

Band 17q11.2 Start 29,625,938 bp

End29,930,276 bp

Gene location ( Mouse )

Chr.Chromosome 11 (mouse)

Band 11|11 B5 Start 77,107,113 bp

End77,351,046 bp

RNA expression pattern

HumanMouse (ortholog)tibialis anterior muscle deltoid muscle cardiac muscle tissue of right atrium blood Skeletal muscle tissue of rectus abdominis gastrocnemius muscle quadriceps femoris muscle Skeletal muscle tissue of biceps brachii vastus lateralis muscle white blood cellspermatocyte extraocular muscle digastric muscle temporal muscle sternocleidomastoid muscle interventricular septum soleus muscle vastus lateralis muscle triceps brachii muscle lymph node

Human Mouse (ortholog)

tibialis anterior muscle deltoid muscle cardiac muscle tissue of right atrium blood Skeletal muscle tissue of rectus abdominis gastrocnemius muscle quadriceps femoris muscle Skeletal muscle tissue of biceps brachii vastus lateralis muscle white blood cellspermatocyte extraocular muscle digastric muscle temporal muscle sternocleidomastoid muscle interventricular septum soleus muscle vastus lateralis muscle triceps brachii muscle lymph node

spermatocyte extraocular muscle digastric muscle temporal muscle sternocleidomastoid muscle interventricular septum soleus muscle vastus lateralis muscle triceps brachii muscle lymph node

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Protein phosphatase Slingshot homolog 2 is an enzyme that in humans is encoded by the SSH2 gene.

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002).[supplied by OMIM]

External links

Overview of all the structural information available in the PDB for UniProt: (Protein phosphatase Slingshot homolog 2) at the PDBe-KB.

SSH2

Further reading

External links