SSH3

Identifiers

Aliases, SSH3L, slingshot protein phosphatase 3

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 11 (human)

Band 11q13.2 Start 67,303,478 bp

End67,312,607 bp

Gene location ( Mouse )

Chr.Chromosome 19 (mouse)

Band 19|19 A Start 4,311,696 bp

End4,319,208 bp

RNA expression pattern

HumanMouse (ortholog)pancreatic ductal cell right hemisphere of cerebellum minor salivary glands right uterine tube mucosa of transverse colon vagina skin of leg ectocervix skin of abdomen gastric mucosagranulocyte lip esophagus primary visual cortex superior frontal gyrus cerebellar cortex stomach colon neural layer of retina duodenum

Human Mouse (ortholog)

pancreatic ductal cell right hemisphere of cerebellum minor salivary glands right uterine tube mucosa of transverse colon vagina skin of leg ectocervix skin of abdomen gastric mucosagranulocyte lip esophagus primary visual cortex superior frontal gyrus cerebellar cortex stomach colon neural layer of retina duodenum

pancreatic ductal cell right hemisphere of cerebellum minor salivary glands right uterine tube mucosa of transverse colon vagina skin of leg ectocervix skin of abdomen gastric mucosa

granulocyte lip esophagus primary visual cortex superior frontal gyrus cerebellar cortex stomach colon neural layer of retina duodenum

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Protein phosphatase Slingshot homolog 3 is an enzyme that in humans is encoded by the SSH3 gene.

Function

The ADF (actin-depolymerizing factor)/cofilin family (see MIM 601442) is composed of stimulus-responsive mediators of actin dynamics. ADF/cofilin proteins are inactivated by kinases such as LIM domain kinase-1 (LIMK1; MIM 601329). The SSH family appears to play a role in actin dynamics by reactivating ADF/cofilin proteins in vivo (Niwa et al., 2002).[supplied by OMIM]

SSH3

Function

Further reading