Steven J. Burakoff is a cancer specialist and the author of both Therapeutic Immunology (2001) and Graft-Vs.-Host Disease: Immunology, Pathophysiology, and Treatment (1990). He served as Director of The Tisch Cancer Institute at Mount Sinai (2007-2017), which was created in 2007 to focus on translational medicine. He is the Lillian and Henry M. Stratton Professor of Cancer Medicine at Mount Sinai Medical Center as well as Dean for Cancer Innovation and Chief, Pediatric Oncology at the Icahn School of Medicine.

Biography

Before joining Mount Sinai, he was recruited by New York University School of Medicine to revitalize the research and treatment mission of NYU's Cancer Institute, which during his tenure experienced a 31 percent growth and a 50 percent increase in funding from the National Cancer Institute. He completed a residency in medicine at New York Hospital-Cornell Medical Center and pursued fellowships in immunology at both Rockefeller University and Harvard Medical School.

He has received 84 grants as of 2020 in fields related to core administration, cancer, T-Cell activation and regulation, as well as various immunological studies.

His brother, Robert Burakoff, is a gastroenterologist at Brigham and Women's Hospital in Boston, MA.[citation needed]

Awards

Appointments and positions

Publications

Burakoff has published 404 articles as of 2020 and has been cited more than 23,000 times according to RearchGate.

Books

  • Strom TB, Austen KF, Burakoff SJ. Therapeutic Immunology. Wiley-Blackwell, 2001 ISBN 0-632-04359-8
  • Ferrara JLM, Deeg HJ, Burakoff SJ. Graft-Vs.-Host Disease: Immunology, Pathophysiology, and Treatment. Marcel Dekker, 1990 ISBN 0-8247-9728-0

Other publications (partial list)

  • Pyarajan, S; Matejovic, G; Pratt, JC; Baksh, S; Burakoff, SJ (August 2008). . J. Biol. Chem. 283 (35): 23505–9. doi:. PMC . PMID .
  • Jin, YJ; Cai, CY; Zhang, X; Burakoff, SJ (June 2008). "Lysine 144, a ubiquitin attachment site in HIV-1 Nef, is required for Nef-mediated CD4 down-regulation". J. Immunol. 180 (12): 7878–86. doi:. PMID .
  • Sawasdikosol, S; Pyarajan, S; Alzabin, S; Matejovic, G; Burakoff, SJ (November 2007). . J. Biol. Chem. 282 (48): 34693–9. doi:. PMID .
  • Mathew, JP; Taylor, BS; Bader, GD; et al. (February 2007). . PLOS Comput. Biol. 3 (2): e12. Bibcode:. doi:. PMC . PMID .
  • Fragoso, RC; Pyarajan, S; Irie, HY; Burakoff, SJ (November 2006). "A CD8/Lck transgene is able to drive thymocyte differentiation". J. Immunol. 177 (9): 6007–17. doi:. PMID .
  • Jin, YJ; Cai, CY; Zhang, X; Zhang, HT; Hirst, JA; Burakoff, SJ (September 2005). "HIV Nef-mediated CD4 down-regulation is adaptor protein complex 2 dependent". J. Immunol. 175 (5): 3157–64. doi:. PMID .
  • Jin, YJ; Zhang, X; Boursiquot, JG; Burakoff, SJ (November 2004). "CD4 phosphorylation partially reverses Nef down-regulation of CD4". J. Immunol. 173 (9): 5495–500. doi:. PMID .
  • Frazer-Abel, AA; Baksh, S; Fosmire, SP; et al. (November 2004). "Nicotine activates nuclear factor of activated T cells c2 (NFATc2) and prevents cell cycle entry in T cells". J. Pharmacol. Exp. Ther. 311 (2): 758–69. doi:. PMID .
  • Friedman, JS; Lopez, MF; Fleming, MD; et al. (October 2004). "SOD2-deficiency anemia: protein oxidation and altered protein expression reveal targets of damage, stress response, and antioxidant responsiveness". Blood. 104 (8): 2565–73. doi:. PMID .
  • Su, MW; Pyarajan, S; Chang, JH; et al. (September 2004). "Fratricide of CD8+ cytotoxic T lymphocytes is dependent on cellular activation and perforin-mediated killing". Eur. J. Immunol. 34 (9): 2459–70. doi:. PMID .
  • Friedman, JS; Alpdogan, O; van den Brink, MR; et al. (July 2004). . Biol. Blood Marrow Transplant. 10 (7): 448–60. doi:. PMID .
  • Slavik, JM; Lim, DG; Burakoff, SJ; Hafler, DA (January 2004). . J. Biol. Chem. 279 (2): 910–9. doi:. PMID .

External links