TGIF2

Identifiers

Aliases, TGFB induced factor homeobox 2

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 20 (human)

Band 20q11.23 Start 36,573,488 bp

End36,593,950 bp

Gene location ( Mouse )

Chr.Chromosome 2 (mouse)

Band 2|2 H1 Start 156,681,927 bp

End156,697,490 bp

RNA expression pattern

HumanMouse (ortholog)ventricular zone embryo ganglionic eminence sural nerve gonad buccal mucosa cell granulocyte right uterine tube testicle monocyteventricular zone zygote phalanx of finger epiblast tail of embryo genital tubercle embryo thumb mandibular prominence maxillary prominence

Human Mouse (ortholog)

ventricular zone embryo ganglionic eminence sural nerve gonad buccal mucosa cell granulocyte right uterine tube testicle monocyteventricular zone zygote phalanx of finger epiblast tail of embryo genital tubercle embryo thumb mandibular prominence maxillary prominence

ventricular zone embryo ganglionic eminence sural nerve gonad buccal mucosa cell granulocyte right uterine tube testicle monocyte

ventricular zone zygote phalanx of finger epiblast tail of embryo genital tubercle embryo thumb mandibular prominence maxillary prominence

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Homeobox protein TGIF2 is a protein that in humans is encoded by the TGIF2 gene.

The protein encoded by this gene is a DNA-binding homeobox protein and a transcriptional repressor. The encoded protein appears to repress transcription by recruiting histone deacetylases to TGF beta-responsive genes. This gene is amplified and overexpressed in some ovarian cancers, and mutations in this gene can cause holoprosencephaly.

TGIF2

Further reading