TOB2

Identifiers

Aliases, TOB4, TOBL, TROB2, transducer of ERBB2, 2, APRO5

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 22 (human)

Band 22q13.2 Start 41,433,494 bp

End41,446,801 bp

Gene location ( Mouse )

Chr.Chromosome 15 (mouse)

Band 15|15 E1 Start 81,732,473 bp

End81,742,997 bp

RNA expression pattern

HumanMouse (ortholog)optic nerve paraflocculus of cerebellum gastric mucosa mucosa of paranasal sinus muscle of thigh popliteal artery tibial arteries gastrocnemius muscle right hemisphere of cerebellum Skeletal muscle tissue of rectus abdominisascending aorta aortic valve retinal pigment epithelium ciliary body neural layer of retina brown adipose tissue epithelium of lens medial head of gastrocnemius muscle primary oocyte masseter muscle

Human Mouse (ortholog)

optic nerve paraflocculus of cerebellum gastric mucosa mucosa of paranasal sinus muscle of thigh popliteal artery tibial arteries gastrocnemius muscle right hemisphere of cerebellum Skeletal muscle tissue of rectus abdominisascending aorta aortic valve retinal pigment epithelium ciliary body neural layer of retina brown adipose tissue epithelium of lens medial head of gastrocnemius muscle primary oocyte masseter muscle

ascending aorta aortic valve retinal pigment epithelium ciliary body neural layer of retina brown adipose tissue epithelium of lens medial head of gastrocnemius muscle primary oocyte masseter muscle

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Protein Tob2 (transducer of ERBB2, 2) is a protein that in humans is encoded by the TOB2 gene.

TOB2 belongs to the TOB (see TOB1; MIM 605523)/BTG1 (MIM 109580) family of antiproliferative proteins, which are involved in the regulation of cell cycle progression.[supplied by OMIM]

Interactions

TOB2 has been shown to interact with CNOT7.

TOB2

Interactions

Further reading