TXNDC12

Available structuresPDBOrtholog search:List of PDB id codes,

Available structures

PDBOrtholog search:

List of PDB id codes,

List of PDB id codes

Identifiers

Aliases, AG1, AGR1, ERP16, ERP18, ERP19, PDIA16, TLP19, hAG-1, hTLP19, thioredoxin domain containing 12

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1p32.3 Start 52,020,131 bp

End52,055,191 bp

Gene location ( Mouse )

Chr.Chromosome 4 (mouse)

Band 4|4 C7 Start 108,691,798 bp

End108,719,324 bp

RNA expression patternHumanMouse (ortholog)monocyte rectum gonad stromal cell of endometrium body of pancreas islet of Langerhans ventricular zone placenta gallbladder olfactory zone of nasal mucosamedial ganglionic eminence spermatocyte endocardial cushion dermis calvaria epithelium of lens atrium efferent ductule atrioventricular valve yolk sacn/a

RNA expression pattern

HumanMouse (ortholog)monocyte rectum gonad stromal cell of endometrium body of pancreas islet of Langerhans ventricular zone placenta gallbladder olfactory zone of nasal mucosamedial ganglionic eminence spermatocyte endocardial cushion dermis calvaria epithelium of lens atrium efferent ductule atrioventricular valve yolk sac

Human Mouse (ortholog)

monocyte rectum gonad stromal cell of endometrium body of pancreas islet of Langerhans ventricular zone placenta gallbladder olfactory zone of nasal mucosamedial ganglionic eminence spermatocyte endocardial cushion dermis calvaria epithelium of lens atrium efferent ductule atrioventricular valve yolk sac

monocyte rectum gonad stromal cell of endometrium body of pancreas islet of Langerhans ventricular zone placenta gallbladder olfactory zone of nasal mucosa

medial ganglionic eminence spermatocyte endocardial cushion dermis calvaria epithelium of lens atrium efferent ductule atrioventricular valve yolk sac

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Thioredoxin domain-containing protein 12 is a protein that in humans is encoded by the TXNDC12 gene.

TXNDC12 belongs to the thioredoxin superfamily (see TXN; MIM 187700). Members of this superfamily possess a thioredoxin fold with a consensus active-site sequence (CxxC) and have roles in redox regulation, defense against oxidative stress, refolding of disulfide-containing proteins, and regulation of transcription factors (Liu et al., 2003).[supplied by OMIM]

TXNDC12

Further reading