Twist is an unincorporated community in Cross County, Arkansas, United States. Twist was named after a nearby plantation of the same name.

Twist was mentioned in the B.B. King song "Lucille" as the location of a club where he once played. It was at this club in Twist where two men started a fight over a woman named Lucille which set the place on fire. Because of this incident, King named his guitar Lucille.[citation needed]

The blues musician Little Mack Simmons (1933–2000) was born in Twist.

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35°22′34″N 90°30′26″W/35.37611°N 90.50722°W/ 35.37611; -90.50722