UFSP1

Identifiers

Aliases, UFSP, UFM1-specific peptidase 1 (inactive), UFM1 specific peptidase 1 (inactive)

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 7 (human)

Band 7q22.1 Start 100,888,721 bp

End100,889,715 bp

Gene location ( Mouse )

Chr.Chromosome 5 (mouse)

Band 5 G2|5 76.33 cM Start 137,292,891 bp

End137,293,927 bp

RNA expression patternHumanMouse (ortholog)gonad muscle of thigh stromal cell of endometrium gastrocnemius muscle mucosa of transverse colon right adrenal cortex granulocyte left adrenal cortex skeletal muscle tissue right lobe of liverbone marrow quadriceps femoris muscle skeletal muscle tissue proximal tubule muscle of thigh thoracic diaphragm striatum of neuraxis neural layer of retina hypothalamus muscle of armn/a

RNA expression pattern

HumanMouse (ortholog)gonad muscle of thigh stromal cell of endometrium gastrocnemius muscle mucosa of transverse colon right adrenal cortex granulocyte left adrenal cortex skeletal muscle tissue right lobe of liverbone marrow quadriceps femoris muscle skeletal muscle tissue proximal tubule muscle of thigh thoracic diaphragm striatum of neuraxis neural layer of retina hypothalamus muscle of arm

Human Mouse (ortholog)

gonad muscle of thigh stromal cell of endometrium gastrocnemius muscle mucosa of transverse colon right adrenal cortex granulocyte left adrenal cortex skeletal muscle tissue right lobe of liverbone marrow quadriceps femoris muscle skeletal muscle tissue proximal tubule muscle of thigh thoracic diaphragm striatum of neuraxis neural layer of retina hypothalamus muscle of arm

gonad muscle of thigh stromal cell of endometrium gastrocnemius muscle mucosa of transverse colon right adrenal cortex granulocyte left adrenal cortex skeletal muscle tissue right lobe of liver

bone marrow quadriceps femoris muscle skeletal muscle tissue proximal tubule muscle of thigh thoracic diaphragm striatum of neuraxis neural layer of retina hypothalamus muscle of arm

n/a

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

UFM1 specific peptidase 1 (inactive) is a protein that in humans is encoded by the UFSP1 gene.

Function

This gene encodes a protein that is similar to other Ufm1-specific proteases. Studies in mouse determined that Ufsp1 releases Ufm1 (ubiquitin-fold modifier 1) from its bound conjugated complexes which also makes it into an active form. Because the human UFSP1 protein is shorter on the N-terminus and lacks a conserved Cys active site, it is predicted to be non-functional.[provided by RefSeq, Nov 2009].

This article incorporates text from the United States National Library of Medicine, which is in the public domain.