VAMP4

Identifiers

Aliases, VAMP-4, VAMP24, vesicle associated membrane protein 4

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 1 (human)

Band 1q24.3 Start 171,700,160 bp

End171,742,074 bp

Gene location ( Mouse )

Chr.Chromosome 1 (mouse)

Band 1 H2.1|1 70.29 cM Start 162,398,084 bp

End162,426,653 bp

RNA expression pattern

HumanMouse (ortholog)endothelial cell Brodmann area 23 middle temporal gyrus dorsal motor nucleus of vagus nerve inferior olivary nucleus pons pars compacta lateral nuclear group of thalamus cerebellar vermis tibiagastrula supraoptic nucleus pituitary gland motor neuron decidua Epithelium of choroid plexus dorsomedial hypothalamic nucleus lateral septal nucleus islet of Langerhans paraventricular nucleus of hypothalamus

Human Mouse (ortholog)

endothelial cell Brodmann area 23 middle temporal gyrus dorsal motor nucleus of vagus nerve inferior olivary nucleus pons pars compacta lateral nuclear group of thalamus cerebellar vermis tibiagastrula supraoptic nucleus pituitary gland motor neuron decidua Epithelium of choroid plexus dorsomedial hypothalamic nucleus lateral septal nucleus islet of Langerhans paraventricular nucleus of hypothalamus

endothelial cell Brodmann area 23 middle temporal gyrus dorsal motor nucleus of vagus nerve inferior olivary nucleus pons pars compacta lateral nuclear group of thalamus cerebellar vermis tibia

gastrula supraoptic nucleus pituitary gland motor neuron decidua Epithelium of choroid plexus dorsomedial hypothalamic nucleus lateral septal nucleus islet of Langerhans paraventricular nucleus of hypothalamus

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Vesicle-associated membrane protein 4 is a protein that in humans is encoded by the VAMP4 gene.

Function

Synaptobrevins/VAMPs, syntaxins, and the 25-kD synaptosomal-associated protein SNAP25 are the main components of a protein complex involved in the docking and/or fusion of synaptic vesicles with the presynaptic membrane. The protein encoded by this gene is a member of the vesicle-associated membrane protein (VAMP)/synaptobrevin family. This protein may play a role in trans-Golgi network-to-endosome transport.

Interactions

VAMP4 has been shown to interact with AP1M1, STX6 and STX16.

VAMP4

Function

Interactions

Further reading