XPO6

Identifiers

Aliases, EXP6, RANBP20, exportin 6

External IDsOMIM: ; MGI: ; HomoloGene: ; GeneCards: ; OMA:

Gene location ( Human )

Chr.Chromosome 16 (human)

Band 16p12.1 Start 28,097,976 bp

End28,211,965 bp

Gene location ( Mouse )

Chr.Chromosome 7 (mouse)

Band 7|7 F3 Start 125,700,887 bp

End125,799,673 bp

RNA expression pattern

HumanMouse (ortholog)blood granulocyte left testis right testis spleen epithelium of colon C1 segment tibial nerve upper lobe of left lung right frontal lobetail of embryo genital tubercle granulocyte spermatocyte dentate gyrus of hippocampal formation granule cell ventricular zone spermatid yolk sac epiblast seminiferous tubule

Human Mouse (ortholog)

blood granulocyte left testis right testis spleen epithelium of colon C1 segment tibial nerve upper lobe of left lung right frontal lobetail of embryo genital tubercle granulocyte spermatocyte dentate gyrus of hippocampal formation granule cell ventricular zone spermatid yolk sac epiblast seminiferous tubule

blood granulocyte left testis right testis spleen epithelium of colon C1 segment tibial nerve upper lobe of left lung right frontal lobe

tail of embryo genital tubercle granulocyte spermatocyte dentate gyrus of hippocampal formation granule cell ventricular zone spermatid yolk sac epiblast seminiferous tubule

Gene ontologyMolecular functionCellular componentBiological processSources: /

Gene ontology

Molecular function

Cellular component

Biological process

Sources: /

OrthologsSpeciesHumanMouseEntrez Ensembl UniProtRefSeq (mRNA)RefSeq (protein)Location (UCSC)PubMed search

Orthologs

Species Human Mouse

Entrez

Ensembl

UniProt

RefSeq (mRNA)

RefSeq (protein)

Location (UCSC)

PubMed search

Wikidata

View/Edit HumanView/Edit Mouse

Exportin-6 is a protein that in humans is encoded by the XPO6 gene.

Exportins, such as XPO6, recruit cargo in the nucleoplasm in the presence of Ran-GTP and form ternary export complexes. These complexes are transported through nuclear pore complexes to the cytoplasm, where GTP is hydrolyzed and the export complex is disassembled.

XPO6

Further reading