C30-NBOMe
In-game article clicks load inline without leaving the challenge.
C30-NBOMe, or 30C-NBOMe, also known as N-(3,4,5-trimethoxybenzyl)-4-chloro-2,5-dimethoxyphenethylamine or as 25C-NB345OMe, is a serotonin receptor modulator of the phenethylamine, 2C, and 25-NB (NBOMe) families. It is an analogue of 25C-NBOMe with three methoxy groups on the benzyl ring, located at the 3, 4, and 5 positions. The drug was encountered as a novel designer drug in Sweden in 2013. However, C30-NBOMe showed greater than or equal to 1,000-fold lower potency as a serotonin 5-HT2A receptor agonist in vitro compared to conventional 25-NB drugs like 25I-NBOMe and 25B-NBOMe (EC50Tooltip half-maximal effective concentration = 1,251nM vs. 0.40–1.2nM, respectively). Its affinity for the serotonin 5-HT2A receptor was similarly low (Ki = 515nM, versus 0.82nM for 25C-NBOMe). The chemical identification of C30-NBOMe has been studied and described.