RCOR1

REST corepressor 1 also known as CoREST is a protein that in humans is encoded by the RCOR1 gene.

Function

This gene encodes a protein that is well-conserved, downregulated at birth, and with a specific role in determining neural cell differentiation. The encoded protein binds to the C-terminal domain of REST (repressor element-1 silencing transcription factor).

Interactions

RCOR1 has been shown to interact with

• HDAC1,
• HDAC2,
• HMG20B,
• REST and
• PHF21A.

Further reading

This article incorporates text from the United States National Library of Medicine, which is in the public domain.