SIN3A

Paired amphipathic helix protein Sin3a is a protein that in humans is encoded by the SIN3A gene.

Function

The protein encoded by this gene is a transcriptional regulatory protein. It contains paired amphipathic helix (PAH) domains, which are important for protein-protein interactions and may mediate repression by the Mad-Max complex.

Interactions

SIN3A has been shown to interact with:

• CABIN1
• HBP1,
• HDAC1,
• HDAC9,
• Histone deacetylase 2,
• Host cell factor C1,
• IKZF1,
• ING1,
• KLF11,
• MNT,
• MXD1,
• Methyl-CpG-binding domain protein 2,
• Nuclear receptor co-repressor 2,
• OGT,
• PHF12,
• Promyelocytic leukemia protein,
• RBBP4,
• RBBP7,
• SAP130,
• SAP30,
• SMARCA2,
• SMARCA4,
• SMARCC1,
• SUDS3,
• TAL1, and
• Zinc finger and BTB domain-containing protein 16.

See also

• Transcription coregulator

Further reading

External links

• at the U.S. National Library of Medicine Medical Subject Headings (MeSH)
• FactorBook

This article incorporates text from the United States National Library of Medicine, which is in the public domain.